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Filamin B Regulates Chondrocyte Proliferation and Differentiation through Cdk1 Signaling
Humans who harbor loss of function mutations in the actin-associated filamin B (FLNB) gene develop spondylocarpotarsal syndrome (SCT), a disorder characterized by dwarfism (delayed bone formation) and premature fusion of the vertebral, carpal and tarsal bones (premature differentiation). To better u...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925234/ https://www.ncbi.nlm.nih.gov/pubmed/24551245 http://dx.doi.org/10.1371/journal.pone.0089352 |