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Phosphorylated Mnk1 and eIF4E Are Associated with Lymph Node Metastasis and Poor Prognosis of Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma (NPC) is a head and neck malignant tumor rare throughout most of the world but common in Southeast Asia, especially in Southern China. The phosphorylation of eukaryotic translation initiation factor 4E (eIF4E) by MAP kinase-interacting kinases (Mnk) on Ser-209 promotes cellu...

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Detalles Bibliográficos
Autores principales: Zheng, Jun, Li, Jiao, Xu, Lina, Xie, Guiyuan, Wen, Qiuyuan, Luo, Jiadi, Li, Duo, Huang, Donghai, Fan, Songqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925237/
https://www.ncbi.nlm.nih.gov/pubmed/24551240
http://dx.doi.org/10.1371/journal.pone.0089220