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Lipid overloading during liver regeneration causes delayed hepatocyte DNA replication by increasing ER stress in mice with simple hepatic steatosis
BACKGROUND AND AIM: Impaired fatty liver regeneration has already been reported in many genetic modification models. However, in diet-induced simple hepatic steatosis, which showed similar phenotype with clinical pathology, whether liver regeneration is impaired or not remains unclear. In this study...
Autores principales: | Hamano, Mina, Ezaki, Hisao, Kiso, Shinichi, Furuta, Kunimaro, Egawa, Mayumi, Kizu, Takashi, Chatani, Norihiro, Kamada, Yoshihiro, Yoshida, Yuichi, Takehara, Tetsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925298/ https://www.ncbi.nlm.nih.gov/pubmed/23512345 http://dx.doi.org/10.1007/s00535-013-0780-7 |
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