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Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells
Topoisomerase IIbeta (Top2b) is an enzyme that modulates DNA supercoiling by catalyzing the passage of DNA duplexes through one another. It is ubiquitously expressed in postmitotic cells and known to function during the development of neuromuscular junctions in the diaphragm and the proper formation...
Autores principales: | Li, Ying, Hao, Hailing, Tzatzalos, Evangeline, Lin, Ren-Kuo, Doh, Sungtae, Liu, Leroy F., Lyu, Yi Lisa, Cai, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925320/ https://www.ncbi.nlm.nih.gov/pubmed/24463367 http://dx.doi.org/10.1242/bio.20146767 |
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