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Impact of heterozygote CFTR Mutations in COPD patients with Chronic Bronchitis

BACKGROUND: Cigarette smoking causes Chronic Obstructive Pulmonary Disease (COPD), the 3rd leading cause of death in the U.S. CFTR ion transport dysfunction has been implicated in COPD pathogenesis, and is associated with chronic bronchitis. However, susceptibility to smoke induced lung injury is va...

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Detalles Bibliográficos
Autores principales:	Raju, S Vamsee, Tate, Jody H, Peacock, Sandra KG, Fang, Ping, Oster, Robert A, Dransfield, Mark T, Rowe, Steven M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925354/ https://www.ncbi.nlm.nih.gov/pubmed/24517344 http://dx.doi.org/10.1186/1465-9921-15-18

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