Doing the math: How yeast cells maintain their peroxisome populations

The formation of membrane contact sites between cellular organelles is required for proper organelle communication and maintenance in the compartmentalized eukaryotic cell. We recently identified a tether that links peroxisomes to the cortical ER in the yeast, Saccharomyces cerevisiae. The tether is...

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Detalles Bibliográficos
Autores principales: Knoblach, Barbara, Rachubinski, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Article Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925452/
https://www.ncbi.nlm.nih.gov/pubmed/24567780
http://dx.doi.org/10.4161/cib.26901
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author Knoblach, Barbara
Rachubinski, Richard A
author_facet Knoblach, Barbara
Rachubinski, Richard A
author_sort Knoblach, Barbara
collection PubMed
description The formation of membrane contact sites between cellular organelles is required for proper organelle communication and maintenance in the compartmentalized eukaryotic cell. We recently identified a tether that links peroxisomes to the cortical ER in the yeast, Saccharomyces cerevisiae. The tether is made up of the peroxisome biogenic protein Pex3p and the peroxisome inheritance factor Inp1p, and is formed by Inp1p-mediated linkage of ER-bound Pex3p and peroxisomal Pex3p. Here we discuss how this tether is fine-tuned to ensure that peroxisomes are stably maintained over generations of yeast cells.
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spelling pubmed-39254522014-02-24 Doing the math: How yeast cells maintain their peroxisome populations Knoblach, Barbara Rachubinski, Richard A Commun Integr Biol Article Addendum The formation of membrane contact sites between cellular organelles is required for proper organelle communication and maintenance in the compartmentalized eukaryotic cell. We recently identified a tether that links peroxisomes to the cortical ER in the yeast, Saccharomyces cerevisiae. The tether is made up of the peroxisome biogenic protein Pex3p and the peroxisome inheritance factor Inp1p, and is formed by Inp1p-mediated linkage of ER-bound Pex3p and peroxisomal Pex3p. Here we discuss how this tether is fine-tuned to ensure that peroxisomes are stably maintained over generations of yeast cells. Landes Bioscience 2013-11-01 2013-11-13 /pmc/articles/PMC3925452/ /pubmed/24567780 http://dx.doi.org/10.4161/cib.26901 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Article Addendum
Knoblach, Barbara
Rachubinski, Richard A
Doing the math: How yeast cells maintain their peroxisome populations
title Doing the math: How yeast cells maintain their peroxisome populations
title_full Doing the math: How yeast cells maintain their peroxisome populations
title_fullStr Doing the math: How yeast cells maintain their peroxisome populations
title_full_unstemmed Doing the math: How yeast cells maintain their peroxisome populations
title_short Doing the math: How yeast cells maintain their peroxisome populations
title_sort doing the math: how yeast cells maintain their peroxisome populations
topic Article Addendum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925452/
https://www.ncbi.nlm.nih.gov/pubmed/24567780
http://dx.doi.org/10.4161/cib.26901
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