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Modulation of c-Fos and BDNF Protein Expression in Pentylenetetrazole-Kindled Mice following the Treatment with Novel Antiepileptic Compound HHL-6

Brain-derived neurotrophic factor (BDNF) and c-Fos are shown to promote epileptogenesis and are taken as a marker of neuronal activity. The present study investigated the expression of BDNF and c-Fos in mice brain with pentylenetetrazol- (PTZ-) induced generalized seizure and evaluated the effect of...

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Detalles Bibliográficos
Autores principales: Malhi, Saima Mahmood, Jawed, Huma, Hanif, Farina, Ashraf, Nadeem, Zubair, Farhat, Siddiqui, Bina S., Begum, Sabira, Kabir, Nurul, Simjee, Shabana Usman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925558/
https://www.ncbi.nlm.nih.gov/pubmed/24605339
http://dx.doi.org/10.1155/2014/876712