Brd4 and HEXIM1: Multiple Roles in P-TEFb Regulation and Cancer

Bromodomain-containing protein 4 (Brd4) and hexamethylene bisacetamide (HMBA) inducible protein 1 (HEXIM1) are two opposing regulators of the positive transcription elongation factor b (P-TEFb), which is the master modulator of RNA polymerase II during transcriptional elongation. While Brd4 recruits...

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Detalles Bibliográficos
Autores principales: Chen, Ruichuan, Yik, Jasper H. N., Lew, Qiao Jing, Chao, Sheng-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925632/
https://www.ncbi.nlm.nih.gov/pubmed/24592384
http://dx.doi.org/10.1155/2014/232870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925632/
https://www.ncbi.nlm.nih.gov/pubmed/24592384
http://dx.doi.org/10.1155/2014/232870

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