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UBF complexes with phosphatidylinositol 4,5-bisphosphate in nucleolar organizer regions regardless of ongoing RNA polymerase I activity
To maintain growth and division, cells require a large-scale production of rRNAs which occurs in the nucleolus. Recently, we have shown the interaction of nucleolar phosphatidylinositol 4,5-bisphosphate (PIP2) with proteins involved in rRNA transcription and processing, namely RNA polymerase I (Pol...
Autores principales: | Sobol, Margarita, Yildirim, Sukriye, Philimonenko, Vlada V, Marášek, Pavel, Castaño, Enrique, Hozák, Pavel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925692/ https://www.ncbi.nlm.nih.gov/pubmed/24513678 http://dx.doi.org/10.4161/nucl.27154 |
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