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On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis
Meiotic recombination plays a critical role in achieving accurate chromosome segregation and increasing genetic diversity. Many studies, mostly in yeast, have provided important insights into the coordination and interplay between the proteins involved in the homologous recombination pathway, especi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925842/ https://www.ncbi.nlm.nih.gov/pubmed/24596572 http://dx.doi.org/10.3389/fpls.2014.00023 |
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author | Pradillo, Mónica Varas, Javier Oliver, Cecilia Santos, Juan L. |
author_facet | Pradillo, Mónica Varas, Javier Oliver, Cecilia Santos, Juan L. |
author_sort | Pradillo, Mónica |
collection | PubMed |
description | Meiotic recombination plays a critical role in achieving accurate chromosome segregation and increasing genetic diversity. Many studies, mostly in yeast, have provided important insights into the coordination and interplay between the proteins involved in the homologous recombination pathway, especially the recombinase RAD51 and the meiosis-specific DMC1. Here we summarize the current progresses on the function of both recombinases and the CX3 complex encoded by AtRAD51 paralogs, in the plant model species Arabidopsis thaliana. Similarities and differences respect to the function of these proteins in other organisms are also indicated. |
format | Online Article Text |
id | pubmed-3925842 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-39258422014-03-04 On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis Pradillo, Mónica Varas, Javier Oliver, Cecilia Santos, Juan L. Front Plant Sci Plant Science Meiotic recombination plays a critical role in achieving accurate chromosome segregation and increasing genetic diversity. Many studies, mostly in yeast, have provided important insights into the coordination and interplay between the proteins involved in the homologous recombination pathway, especially the recombinase RAD51 and the meiosis-specific DMC1. Here we summarize the current progresses on the function of both recombinases and the CX3 complex encoded by AtRAD51 paralogs, in the plant model species Arabidopsis thaliana. Similarities and differences respect to the function of these proteins in other organisms are also indicated. Frontiers Media S.A. 2014-02-17 /pmc/articles/PMC3925842/ /pubmed/24596572 http://dx.doi.org/10.3389/fpls.2014.00023 Text en Copyright © 2014 Pradillo, Varas, Oliver and Santos. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Plant Science Pradillo, Mónica Varas, Javier Oliver, Cecilia Santos, Juan L. On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis |
title | On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis |
title_full | On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis |
title_fullStr | On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis |
title_full_unstemmed | On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis |
title_short | On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis |
title_sort | on the role of atdmc1, atrad51 and its paralogs during arabidopsis meiosis |
topic | Plant Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925842/ https://www.ncbi.nlm.nih.gov/pubmed/24596572 http://dx.doi.org/10.3389/fpls.2014.00023 |
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