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Pseudomonas pyocyanin stimulates IL-8 expression through MAPK and NF-κB pathways in differentiated U937 cells

BACKGROUND: Pyocyanin (PCN), an extracellular product of Pseudomonas aeruginosa and a blue redox active secondary metabolite, plays an important role in invasive pulmonary infection. However, the detailed inflammatory response triggered by PCN infection in inflammatory cells (particularly macrophage...

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Detalles Bibliográficos
Autores principales: Chai, Wenshu, Zhang, Jia, Duan, Yan, Pan, Dianzhu, Liu, Wei, Li, Ying, Yan, Xue, Chen, Baiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925954/
https://www.ncbi.nlm.nih.gov/pubmed/24499192
http://dx.doi.org/10.1186/1471-2180-14-26