Differential methylation of the TRPA1 promoter in pain sensitivity

Chronic pain is a global public health problem, but the underlying molecular mechanisms are not fully understood. Here we examine genome-wide DNA methylation, first in 50 identical twins discordant for heat pain sensitivity and then in 50 further unrelated individuals. Whole-blood DNA methylation wa...

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Detalles Bibliográficos
Autores principales: Bell, J.T., Loomis, A.K., Butcher, L.M., Gao, F., Zhang, B., Hyde, C.L., Sun, J., Wu, H., Ward, K., Harris, J., Scollen, S., Davies, M.N., Schalkwyk, L.C., Mill, J., Williams, F.M.K., Li, N., Deloukas, P., Beck, S., McMahon, S.B., Wang, J., John, S.L., Spector, T.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926001/
https://www.ncbi.nlm.nih.gov/pubmed/24496475
http://dx.doi.org/10.1038/ncomms3978

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