Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma

Gonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testoste...

Descripción completa

Detalles Bibliográficos
Autores principales: Thakkar, Astha, Kannan, Subramanian, Hamrahian, Amir, Prayson, Richard A., Weil, Robert J., Faiman, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926319/
https://www.ncbi.nlm.nih.gov/pubmed/24592337
http://dx.doi.org/10.1155/2014/194716
Descripción
Sumario:Gonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testosterone, and elevated levels of gonadotropins. Surgical resection of the tumor resulted in normalization of gonadotropins and fall in serum testosterone to subnormal levels in the postoperative period confirming that the tumor was secreting bioactive luteinizing hormone (LH).

Ejemplares similares