Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma

Gonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testoste...

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Detalles Bibliográficos
Autores principales: Thakkar, Astha, Kannan, Subramanian, Hamrahian, Amir, Prayson, Richard A., Weil, Robert J., Faiman, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926319/
https://www.ncbi.nlm.nih.gov/pubmed/24592337
http://dx.doi.org/10.1155/2014/194716
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author Thakkar, Astha
Kannan, Subramanian
Hamrahian, Amir
Prayson, Richard A.
Weil, Robert J.
Faiman, Charles
author_facet Thakkar, Astha
Kannan, Subramanian
Hamrahian, Amir
Prayson, Richard A.
Weil, Robert J.
Faiman, Charles
author_sort Thakkar, Astha
collection PubMed
description Gonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testosterone, and elevated levels of gonadotropins. Surgical resection of the tumor resulted in normalization of gonadotropins and fall in serum testosterone to subnormal levels in the postoperative period confirming that the tumor was secreting bioactive luteinizing hormone (LH).
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spelling pubmed-39263192014-03-03 Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma Thakkar, Astha Kannan, Subramanian Hamrahian, Amir Prayson, Richard A. Weil, Robert J. Faiman, Charles Case Rep Endocrinol Case Report Gonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testosterone, and elevated levels of gonadotropins. Surgical resection of the tumor resulted in normalization of gonadotropins and fall in serum testosterone to subnormal levels in the postoperative period confirming that the tumor was secreting bioactive luteinizing hormone (LH). Hindawi Publishing Corporation 2014 2014-01-28 /pmc/articles/PMC3926319/ /pubmed/24592337 http://dx.doi.org/10.1155/2014/194716 Text en Copyright © 2014 Astha Thakkar et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Thakkar, Astha
Kannan, Subramanian
Hamrahian, Amir
Prayson, Richard A.
Weil, Robert J.
Faiman, Charles
Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma
title Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma
title_full Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma
title_fullStr Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma
title_full_unstemmed Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma
title_short Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma
title_sort testicular “hyperstimulation” syndrome: a case of functional gonadotropinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926319/
https://www.ncbi.nlm.nih.gov/pubmed/24592337
http://dx.doi.org/10.1155/2014/194716
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AT weilrobertj testicularhyperstimulationsyndromeacaseoffunctionalgonadotropinoma
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