Combined exposure to cigarette smoke and nontypeable Haemophilus influenzae drives development of a COPD phenotype in mice

BACKGROUND: Cigarette smoke (CS) is the major etiologic factor of chronic obstructive pulmonary disease (COPD). CS-exposed mice develop emphysema and mild pulmonary inflammation but no airway obstruction, which is also a prominent feature of COPD. Therefore, CS may interact with other factors, parti...

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Detalles Bibliográficos
Autores principales: Ganesan, Shyamala, Comstock, Adam T, Kinker, Brenton, Mancuso, Peter, Beck, James M, Sajjan, Uma S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926338/
https://www.ncbi.nlm.nih.gov/pubmed/24495712
http://dx.doi.org/10.1186/1465-9921-15-11

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