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Inhibiting the HIV Integration Process: Past, Present, and the Future
[Image: see text] HIV integrase (IN) catalyzes the insertion into the genome of the infected human cell of viral DNA produced by the retrotranscription process. The discovery of raltegravir validated the existence of the IN, which is a new target in the field of anti-HIV drug research. The mechanism...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926363/ https://www.ncbi.nlm.nih.gov/pubmed/24025027 http://dx.doi.org/10.1021/jm400674a |