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Grape seed proanthocyanidin extract protects from cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis

Cisplatin (CP) is used as an antineoplastic drug in the clinic, but its nephrotoxicity limits its use. Grape seed proanthocyanidin extract (GSPE) is a powerful antioxidant. In this study, we investigated whether GSPE can prevent CP-induced nephrotoxicity and explored the underlying mechanism. Male C...

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Detalles Bibliográficos
Autores principales:	GAO, ZHAOLI, LIU, GUANGYI, HU, ZHAO, LI, XING, YANG, XIANGDONG, JIANG, BEI, LI, XIANHUA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926513/ https://www.ncbi.nlm.nih.gov/pubmed/24399449 http://dx.doi.org/10.3892/mmr.2014.1883

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