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Biosensing Using Microring Resonator Interferograms

Optical low-coherence interferometry (OLCI) takes advantage of the variation in refractive index in silicon-wire microring resonator (MRR) effective lengths to perform glucose biosensing using MRR interferograms. The MRR quality factor (Q), proportional to the effective length, could be improved usi...

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Detalles Bibliográficos
Autores principales: Hsu, Shih-Hsiang, Yang, Yung-Chia, Su, Yu-Hou, Wang, Sheng-Min, Huang, Shih-An, Lin, Ching-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926609/
https://www.ncbi.nlm.nih.gov/pubmed/24434876
http://dx.doi.org/10.3390/s140101184
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author Hsu, Shih-Hsiang
Yang, Yung-Chia
Su, Yu-Hou
Wang, Sheng-Min
Huang, Shih-An
Lin, Ching-Yu
author_facet Hsu, Shih-Hsiang
Yang, Yung-Chia
Su, Yu-Hou
Wang, Sheng-Min
Huang, Shih-An
Lin, Ching-Yu
author_sort Hsu, Shih-Hsiang
collection PubMed
description Optical low-coherence interferometry (OLCI) takes advantage of the variation in refractive index in silicon-wire microring resonator (MRR) effective lengths to perform glucose biosensing using MRR interferograms. The MRR quality factor (Q), proportional to the effective length, could be improved using the silicon-wire propagation loss and coupling ratio from the MRR coupler. Our study showed that multimode interference (MMI) performed well in broad band response, but the splitting ratio drifted to 75/25 due to the stress issue. The glucose sensing sensitivity demonstrated 0.00279 meter per refractive-index-unit (RIU) with a Q factor of ∼30,000 under transverse electric polarization. The 1,310 nm DFB laser was built in the OLCI system as the optical ruler achieving 655 nm characterization accuracy. The lowest sensing limitation was therefore 2 × 10(−4) RIU. Moreover, the MRR effective length from the glucose sensitivity could be utilized to experimentally demonstrate the silicon wire effective refractive index with a width of 0.45 μm and height of 0.26 μm.
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spelling pubmed-39266092014-02-18 Biosensing Using Microring Resonator Interferograms Hsu, Shih-Hsiang Yang, Yung-Chia Su, Yu-Hou Wang, Sheng-Min Huang, Shih-An Lin, Ching-Yu Sensors (Basel) Article Optical low-coherence interferometry (OLCI) takes advantage of the variation in refractive index in silicon-wire microring resonator (MRR) effective lengths to perform glucose biosensing using MRR interferograms. The MRR quality factor (Q), proportional to the effective length, could be improved using the silicon-wire propagation loss and coupling ratio from the MRR coupler. Our study showed that multimode interference (MMI) performed well in broad band response, but the splitting ratio drifted to 75/25 due to the stress issue. The glucose sensing sensitivity demonstrated 0.00279 meter per refractive-index-unit (RIU) with a Q factor of ∼30,000 under transverse electric polarization. The 1,310 nm DFB laser was built in the OLCI system as the optical ruler achieving 655 nm characterization accuracy. The lowest sensing limitation was therefore 2 × 10(−4) RIU. Moreover, the MRR effective length from the glucose sensitivity could be utilized to experimentally demonstrate the silicon wire effective refractive index with a width of 0.45 μm and height of 0.26 μm. Molecular Diversity Preservation International (MDPI) 2014-01-10 /pmc/articles/PMC3926609/ /pubmed/24434876 http://dx.doi.org/10.3390/s140101184 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Hsu, Shih-Hsiang
Yang, Yung-Chia
Su, Yu-Hou
Wang, Sheng-Min
Huang, Shih-An
Lin, Ching-Yu
Biosensing Using Microring Resonator Interferograms
title Biosensing Using Microring Resonator Interferograms
title_full Biosensing Using Microring Resonator Interferograms
title_fullStr Biosensing Using Microring Resonator Interferograms
title_full_unstemmed Biosensing Using Microring Resonator Interferograms
title_short Biosensing Using Microring Resonator Interferograms
title_sort biosensing using microring resonator interferograms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926609/
https://www.ncbi.nlm.nih.gov/pubmed/24434876
http://dx.doi.org/10.3390/s140101184
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