SCF(β-TRCP) targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration

Metastasis suppressor 1 (MTSS1) is an important tumor suppressor protein, and loss of MTSS1 expression has been observed in several types of human cancers. Importantly, decreased MTSS1 expression is associated with more aggressive forms of breast and prostate cancers, and with poor survival rate. Cu...

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Detalles Bibliográficos
Autores principales: Zhong, Jiateng, Shaik, Shavali, Wan, Lixin, Tron, Adriana E., Wang, Zhiwei, Sun, Liankun, Inuzuka, Hiroyuki, Wei, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926831/
https://www.ncbi.nlm.nih.gov/pubmed/24318128

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