Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer

Loss of E-cadherin, a hallmark of epithelial-mesenchymal transition (EMT), can significantly affect metastatic dissemination. However, the molecular mechanism of EMT-associated metastatic dissemination by loss of E-cadherin still remains unclear in non-small cell lung cancers (NSCLCs). In the presen...

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Detalles Bibliográficos
Autores principales: Bae, Gab-Yong, Choi, So-Jung, Lee, Ji-Seon, Jo, Jisuk, Lee, Jinseon, Kim, Jhingook, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926845/
https://www.ncbi.nlm.nih.gov/pubmed/24318272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926845/
https://www.ncbi.nlm.nih.gov/pubmed/24318272

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