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Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer

Loss of E-cadherin, a hallmark of epithelial-mesenchymal transition (EMT), can significantly affect metastatic dissemination. However, the molecular mechanism of EMT-associated metastatic dissemination by loss of E-cadherin still remains unclear in non-small cell lung cancers (NSCLCs). In the presen...

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Detalles Bibliográficos
Autores principales:	Bae, Gab-Yong, Choi, So-Jung, Lee, Ji-Seon, Jo, Jisuk, Lee, Jinseon, Kim, Jhingook, Cha, Hyuk-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926845/ https://www.ncbi.nlm.nih.gov/pubmed/24318272

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