Cargando…
Interferon α interferes with immunological tolerance
The ability of regulatory T cells (Tregs) to promote immunological tolerance represents an important obstacle in cancer immunotherapy. We have recently discovered that the clinically established immunotherapeutic agent interferon α (IFNα) inactivates the suppressive functions of human Tregs. Here, w...
Autores principales: | Becker, Christian, Bopp, Tobias, Steinbrink, Kerstin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926876/ https://www.ncbi.nlm.nih.gov/pubmed/24575381 http://dx.doi.org/10.4161/onci.27528 |
Ejemplares similares
-
Interferon α may be back on track to treat acute myeloid leukemia
por: Smits, Evelien L.J.M., et al.
Publicado: (2013) -
Interferons in hematopoiesis and leukemia
por: Schürch, Christian M, et al.
Publicado: (2013) -
IFNα induces prolonged remissions modeling curative immunologic responses in chronic myeloid leukemia
por: Ilander, Mette, et al.
Publicado: (2014) -
Combining targeted therapy with immunotherapy (interferon-α): Rational, efficacy in gastrointestinal stromal tumor model and implications in other malignancies
por: Chen, Lei L., et al.
Publicado: (2012) -
Engineered tumor-infiltrating macrophages as gene delivery vehicles for interferon-α activates immunity and inhibits breast cancer progression
por: Escobar, Giulia, et al.
Publicado: (2014)