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Icariin Decreases the Expression of APP and BACE-1 and Reduces the β-amyloid Burden in an APP Transgenic Mouse Model of Alzheimer's Disease
Objective: The purpose of this study was to investigate the effects and pharmacological mechanisms of icariin, which is the main component in the traditional Chinese herb Epimedium, on β-amyloid (Aβ) production in an amyloid precursor protein (APP) transgenic (Tg) mouse model of Alzheimer's dis...
Autores principales: | Zhang, Lan, Shen, Cong, Chu, Jin, Zhang, Ruyi, Li, Yali, Li, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927130/ https://www.ncbi.nlm.nih.gov/pubmed/24550686 http://dx.doi.org/10.7150/ijbs.6232 |
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