Considerations in perioperative assessment of valproic acid coagulopathy

Valproic acid (VPA) is one of the widely prescribed antiepileptic drugs in children with multiple indications. VPA-induced coagulopathy may occur and constitute a pharmacological and practical challenge affecting pre-operative evaluation and management of patients receiving VPA therapy. This review...

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Detalles Bibliográficos
Autor principal: Abdallah, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927296/
https://www.ncbi.nlm.nih.gov/pubmed/24574585
http://dx.doi.org/10.4103/0970-9185.125685
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author Abdallah, Claude
author_facet Abdallah, Claude
author_sort Abdallah, Claude
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description Valproic acid (VPA) is one of the widely prescribed antiepileptic drugs in children with multiple indications. VPA-induced coagulopathy may occur and constitute a pharmacological and practical challenge affecting pre-operative evaluation and management of patients receiving VPA therapy. This review summarizes the different studies documenting the incidence, severity and available recommendations related to this adverse effect.
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spelling pubmed-39272962014-02-26 Considerations in perioperative assessment of valproic acid coagulopathy Abdallah, Claude J Anaesthesiol Clin Pharmacol Review Article Valproic acid (VPA) is one of the widely prescribed antiepileptic drugs in children with multiple indications. VPA-induced coagulopathy may occur and constitute a pharmacological and practical challenge affecting pre-operative evaluation and management of patients receiving VPA therapy. This review summarizes the different studies documenting the incidence, severity and available recommendations related to this adverse effect. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3927296/ /pubmed/24574585 http://dx.doi.org/10.4103/0970-9185.125685 Text en Copyright: © Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Abdallah, Claude
Considerations in perioperative assessment of valproic acid coagulopathy
title Considerations in perioperative assessment of valproic acid coagulopathy
title_full Considerations in perioperative assessment of valproic acid coagulopathy
title_fullStr Considerations in perioperative assessment of valproic acid coagulopathy
title_full_unstemmed Considerations in perioperative assessment of valproic acid coagulopathy
title_short Considerations in perioperative assessment of valproic acid coagulopathy
title_sort considerations in perioperative assessment of valproic acid coagulopathy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927296/
https://www.ncbi.nlm.nih.gov/pubmed/24574585
http://dx.doi.org/10.4103/0970-9185.125685
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