Oral lesions associated with Nevirapine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases

Stevens–Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely related severe, acute mucocutaneous reactions usually caused by drugs. They are acute life-threatening conditions and cause widespread necrosis of the epithelium. There is persistence of a high risk of SJS or TEN in rela...

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Autores principales: Reddy, Ramana BV, Shekar, P Chandra, Chandra, K Lalith Prakash, Aravind, RS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927350/
https://www.ncbi.nlm.nih.gov/pubmed/24574667
http://dx.doi.org/10.4103/0973-029X.125214
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author Reddy, Ramana BV
Shekar, P Chandra
Chandra, K Lalith Prakash
Aravind, RS
author_facet Reddy, Ramana BV
Shekar, P Chandra
Chandra, K Lalith Prakash
Aravind, RS
author_sort Reddy, Ramana BV
collection PubMed
description Stevens–Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely related severe, acute mucocutaneous reactions usually caused by drugs. They are acute life-threatening conditions and cause widespread necrosis of the epithelium. There is persistence of a high risk of SJS or TEN in relation to human immunodeficiency virus (HIV) infection associated with exposure to nevirapine (NVP). In this article, we present nine cases of SJS and one case of TEN in HIV-seropositive individuals who developed cutaneous, oral, ocular and genital lesions while being treated with NVP.
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spelling pubmed-39273502014-02-26 Oral lesions associated with Nevirapine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases Reddy, Ramana BV Shekar, P Chandra Chandra, K Lalith Prakash Aravind, RS J Oral Maxillofac Pathol Case Report Stevens–Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely related severe, acute mucocutaneous reactions usually caused by drugs. They are acute life-threatening conditions and cause widespread necrosis of the epithelium. There is persistence of a high risk of SJS or TEN in relation to human immunodeficiency virus (HIV) infection associated with exposure to nevirapine (NVP). In this article, we present nine cases of SJS and one case of TEN in HIV-seropositive individuals who developed cutaneous, oral, ocular and genital lesions while being treated with NVP. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3927350/ /pubmed/24574667 http://dx.doi.org/10.4103/0973-029X.125214 Text en Copyright: © Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Reddy, Ramana BV
Shekar, P Chandra
Chandra, K Lalith Prakash
Aravind, RS
Oral lesions associated with Nevirapine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases
title Oral lesions associated with Nevirapine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases
title_full Oral lesions associated with Nevirapine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases
title_fullStr Oral lesions associated with Nevirapine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases
title_full_unstemmed Oral lesions associated with Nevirapine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases
title_short Oral lesions associated with Nevirapine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases
title_sort oral lesions associated with nevirapine-induced stevens–johnson syndrome and toxic epidermal necrolysis: a report of 10 cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927350/
https://www.ncbi.nlm.nih.gov/pubmed/24574667
http://dx.doi.org/10.4103/0973-029X.125214
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