Endoplasmic reticulum stress impairs cholesterol efflux and synthesis in hepatic cells

Metabolic disorders such as type 2 diabetes cause hepatic endoplasmic reticulum (ER) stress, which affects neutral lipid metabolism. However, the role of ER stress in cholesterol metabolism is incompletely understood. Here, we show that induction of acute ER stress in human hepatic HepG2 cells reduc...

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Detalles Bibliográficos
Autores principales: Röhrl, Clemens, Eigner, Karin, Winter, Katharina, Korbelius, Melanie, Obrowsky, Sascha, Kratky, Dagmar, Kovacs, Werner J., Stangl, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927476/
https://www.ncbi.nlm.nih.gov/pubmed/24179149
http://dx.doi.org/10.1194/jlr.M043299

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