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Fabrication of Biochips with Micro Fluidic Channels by Micro End-milling and Powder Blasting
For microfabrications of biochips with micro fluidic channels, a large number of microfabrication techniques based on silicon or glass-based Micro-Electro-Mechanical System (MEMS) technologies were proposed in the last decade. In recent years, for low cost and mass production, polymer-based microfab...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927521/ https://www.ncbi.nlm.nih.gov/pubmed/27879767 |
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author | Yun, Dae Jin Seo, Tae Il Park, Dong Sam |
author_facet | Yun, Dae Jin Seo, Tae Il Park, Dong Sam |
author_sort | Yun, Dae Jin |
collection | PubMed |
description | For microfabrications of biochips with micro fluidic channels, a large number of microfabrication techniques based on silicon or glass-based Micro-Electro-Mechanical System (MEMS) technologies were proposed in the last decade. In recent years, for low cost and mass production, polymer-based microfabrication techniques by microinjection molding and micro hot embossing have been proposed. These techniques, which require a proper photoresist, mask, UV light exposure, developing, and electroplating as a pre-process, are considered to have some problems. In this study, we propose a new microfabrication technology which consists of micro end-milling and powder blasting. This technique could be directly applied to fabricate the metal mold without any preprocesses. The metal mold with micro-channels is machined by micro end-milling, and then, burrs generated in the end-milling process are removed by powder blasting. From the experimental results, micro end-milling combined with powder blasting could be applied effectively for fabrication of the injection mold of biochips with micro fluidic channels. |
format | Online Article Text |
id | pubmed-3927521 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-39275212014-02-18 Fabrication of Biochips with Micro Fluidic Channels by Micro End-milling and Powder Blasting Yun, Dae Jin Seo, Tae Il Park, Dong Sam Sensors (Basel) Full Research Paper For microfabrications of biochips with micro fluidic channels, a large number of microfabrication techniques based on silicon or glass-based Micro-Electro-Mechanical System (MEMS) technologies were proposed in the last decade. In recent years, for low cost and mass production, polymer-based microfabrication techniques by microinjection molding and micro hot embossing have been proposed. These techniques, which require a proper photoresist, mask, UV light exposure, developing, and electroplating as a pre-process, are considered to have some problems. In this study, we propose a new microfabrication technology which consists of micro end-milling and powder blasting. This technique could be directly applied to fabricate the metal mold without any preprocesses. The metal mold with micro-channels is machined by micro end-milling, and then, burrs generated in the end-milling process are removed by powder blasting. From the experimental results, micro end-milling combined with powder blasting could be applied effectively for fabrication of the injection mold of biochips with micro fluidic channels. Molecular Diversity Preservation International (MDPI) 2008-02-22 /pmc/articles/PMC3927521/ /pubmed/27879767 Text en © 2008 by MDPI Reproduction is permitted for noncommercial purposes. |
spellingShingle | Full Research Paper Yun, Dae Jin Seo, Tae Il Park, Dong Sam Fabrication of Biochips with Micro Fluidic Channels by Micro End-milling and Powder Blasting |
title | Fabrication of Biochips with Micro Fluidic Channels by Micro End-milling and Powder Blasting |
title_full | Fabrication of Biochips with Micro Fluidic Channels by Micro End-milling and Powder Blasting |
title_fullStr | Fabrication of Biochips with Micro Fluidic Channels by Micro End-milling and Powder Blasting |
title_full_unstemmed | Fabrication of Biochips with Micro Fluidic Channels by Micro End-milling and Powder Blasting |
title_short | Fabrication of Biochips with Micro Fluidic Channels by Micro End-milling and Powder Blasting |
title_sort | fabrication of biochips with micro fluidic channels by micro end-milling and powder blasting |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927521/ https://www.ncbi.nlm.nih.gov/pubmed/27879767 |
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