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Protein kinase C-delta inactivation inhibits the proliferation and survival of cancer stem cells in culture and in vivo

BACKGROUND: A subpopulation of tumor cells with distinct stem-like properties (cancer stem-like cells, CSCs) may be responsible for tumor initiation, invasive growth, and possibly dissemination to distant organ sites. CSCs exhibit a spectrum of biological, biochemical, and molecular features that ar...

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Detalles Bibliográficos
Autores principales: Chen, Zhihong, Forman, Lora W, Williams, Robert M, Faller, Douglas V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927586/
https://www.ncbi.nlm.nih.gov/pubmed/24528676
http://dx.doi.org/10.1186/1471-2407-14-90