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Protein kinase C-delta inactivation inhibits the proliferation and survival of cancer stem cells in culture and in vivo
BACKGROUND: A subpopulation of tumor cells with distinct stem-like properties (cancer stem-like cells, CSCs) may be responsible for tumor initiation, invasive growth, and possibly dissemination to distant organ sites. CSCs exhibit a spectrum of biological, biochemical, and molecular features that ar...
Autores principales: | Chen, Zhihong, Forman, Lora W, Williams, Robert M, Faller, Douglas V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927586/ https://www.ncbi.nlm.nih.gov/pubmed/24528676 http://dx.doi.org/10.1186/1471-2407-14-90 |
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