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The innervation of the human acetabular labrum and hip joint: an anatomic study
BACKGROUND: The aim of the current study was to evaluate the innervation of the acetabular labrum in the various zones and to understand its potential role in nociception and proprioception in hips with labral pathology. METHODS: A total of twenty hip labrums were tagged and excised intraoperatively...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927620/ https://www.ncbi.nlm.nih.gov/pubmed/24529033 http://dx.doi.org/10.1186/1471-2474-15-41 |
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author | Alzaharani, Abdullah Bali, Kamal Gudena, Ravi Railton, Pamela Ponjevic, Dragana Matyas, John R Powell, James N |
author_facet | Alzaharani, Abdullah Bali, Kamal Gudena, Ravi Railton, Pamela Ponjevic, Dragana Matyas, John R Powell, James N |
author_sort | Alzaharani, Abdullah |
collection | PubMed |
description | BACKGROUND: The aim of the current study was to evaluate the innervation of the acetabular labrum in the various zones and to understand its potential role in nociception and proprioception in hips with labral pathology. METHODS: A total of twenty hip labrums were tagged and excised intraoperatively from patients undergoing a total hip replacement. After preparation, the specimens were cut to a thickness of 10 μm and divided into four quadrants (zones) using a clock face pattern. Neurosensory structure distribution was then evaluated using Hematoxylin and Eosin (H and E), and immunoreactivity to S-100. RESULTS: All specimens had abundant free nerve endings (FNEs). These were seen predominantly superficially and on the chondral side of the labrum. In addition, predominantly three different types of nerve end organs (NEOs) were identified in all twenty specimens. FNEs and NEOs were more frequently seen in the antero-superior and postero-superior zones. Four specimens had abundant vascularity and disorganised architecture of FNEs in the deeper zones of the antero-superior quadrant suggestive of a healed tear. Myofibroblasts were present in abundance in all the labral specimens and were distributed uniformly throughout all labral zones and depth. CONCLUSIONS: The current study shows that the human acetabular labrum has abundant FNEs and NEOs. These are more abundant in the antero-superior and postero-superior zones. The labrum, by virtue of its neural innervation, can potentially mediate pain as well as proprioception of the hip joint, and be involved in neurosecretion that can influence connective tissue repair. |
format | Online Article Text |
id | pubmed-3927620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-39276202014-02-19 The innervation of the human acetabular labrum and hip joint: an anatomic study Alzaharani, Abdullah Bali, Kamal Gudena, Ravi Railton, Pamela Ponjevic, Dragana Matyas, John R Powell, James N BMC Musculoskelet Disord Research Article BACKGROUND: The aim of the current study was to evaluate the innervation of the acetabular labrum in the various zones and to understand its potential role in nociception and proprioception in hips with labral pathology. METHODS: A total of twenty hip labrums were tagged and excised intraoperatively from patients undergoing a total hip replacement. After preparation, the specimens were cut to a thickness of 10 μm and divided into four quadrants (zones) using a clock face pattern. Neurosensory structure distribution was then evaluated using Hematoxylin and Eosin (H and E), and immunoreactivity to S-100. RESULTS: All specimens had abundant free nerve endings (FNEs). These were seen predominantly superficially and on the chondral side of the labrum. In addition, predominantly three different types of nerve end organs (NEOs) were identified in all twenty specimens. FNEs and NEOs were more frequently seen in the antero-superior and postero-superior zones. Four specimens had abundant vascularity and disorganised architecture of FNEs in the deeper zones of the antero-superior quadrant suggestive of a healed tear. Myofibroblasts were present in abundance in all the labral specimens and were distributed uniformly throughout all labral zones and depth. CONCLUSIONS: The current study shows that the human acetabular labrum has abundant FNEs and NEOs. These are more abundant in the antero-superior and postero-superior zones. The labrum, by virtue of its neural innervation, can potentially mediate pain as well as proprioception of the hip joint, and be involved in neurosecretion that can influence connective tissue repair. BioMed Central 2014-02-14 /pmc/articles/PMC3927620/ /pubmed/24529033 http://dx.doi.org/10.1186/1471-2474-15-41 Text en Copyright © 2014 Alzaharani et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Research Article Alzaharani, Abdullah Bali, Kamal Gudena, Ravi Railton, Pamela Ponjevic, Dragana Matyas, John R Powell, James N The innervation of the human acetabular labrum and hip joint: an anatomic study |
title | The innervation of the human acetabular labrum and hip joint: an anatomic study |
title_full | The innervation of the human acetabular labrum and hip joint: an anatomic study |
title_fullStr | The innervation of the human acetabular labrum and hip joint: an anatomic study |
title_full_unstemmed | The innervation of the human acetabular labrum and hip joint: an anatomic study |
title_short | The innervation of the human acetabular labrum and hip joint: an anatomic study |
title_sort | innervation of the human acetabular labrum and hip joint: an anatomic study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927620/ https://www.ncbi.nlm.nih.gov/pubmed/24529033 http://dx.doi.org/10.1186/1471-2474-15-41 |
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