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Implementing lessons learned from previous bronchial biopsy trials in a new randomized controlled COPD biopsy trial with roflumilast

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease mediated by an array of inflammatory cells and mediators, but above all, CD8+ T-lymphocytes, macrophages and neutrophils are important players in disease pathogenesis. Roflumilast, a first-in-class, potent and...

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Detalles Bibliográficos
Autores principales: Barnes, Neil C, Saetta, Marina, Rabe, Klaus F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927659/
https://www.ncbi.nlm.nih.gov/pubmed/24484726
http://dx.doi.org/10.1186/1471-2466-14-9