BMAL1-dependent regulation of the mTOR signaling pathway delays aging

The circadian clock, an internal time-keeping system, has been linked with control of aging, but molecular mechanisms of regulation are not known. BMAL1 is a transcriptional factor and core component of the circadian clock; BMAL1 deficiency is associated with premature aging and reduced lifespan. He...

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Detalles Bibliográficos
Autores principales: Khapre, Rohini V., Kondratova, Anna A., Patel, Sonal, Dubrovsky, Yuliya, Wrobel, Michelle, Antoch, Marina P., Kondratov, Roman V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927809/
https://www.ncbi.nlm.nih.gov/pubmed/24481314

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