Cargando…

Phenethyl isothiocyanate and paclitaxel synergistically enhanced apoptosis and alpha-tubulin hyperacetylation in breast cancer cells

Combination of phenethyl isothiocyanate (PEITC) and paclitaxel (taxol) has been shown to work synergistically to increase apoptosis and cell cycle arrest in breast cancer cells. In this report, we further explored the mechanisms for the synergistic activity of PEITC and taxol in MCF7 and MDA-MB-231...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cang, Shundong, Ma, Yuehua, Chiao, Jen-wei, Liu, Delong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927854/ https://www.ncbi.nlm.nih.gov/pubmed/24495785 http://dx.doi.org/10.1186/2162-3619-3-5

Ejemplares similares

Synergistic effect of paclitaxel and epigenetic agent phenethyl isothiocyanate on growth inhibition, cell cycle arrest and apoptosis in breast cancer cells
por: Liu, Katherine, et al.
Publicado: (2013)

Establishment of prostate cancer spheres from a prostate cancer cell line after phenethyl isothiocyanate treatment and discovery of androgen-dependent reversible differentiation between sphere and neuroendocrine cells
por: Chen, Yamei, et al.
Publicado: (2016)

Dietary Isothiocyanates, Sulforaphane and 2-Phenethyl Isothiocyanate, Effectively Impair Vibrio cholerae Virulence
por: Krause, Klaudyna, et al.
Publicado: (2021)

Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells
por: Kleczka, Anna, et al.
Publicado: (2023)

Phenethyl isothiocyanate activates leptin signaling and decreases food intake
por: Yagi, Miho, et al.
Publicado: (2018)

Phenethyl isothiocyanate and dasatinib combination synergistically reduces hepatocellular carcinoma growth via cell cycle arrest and oxeiptosis
por: Strusi, Gabriele, et al.
Publicado: (2023)

Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells
por: Cang, Shundong, et al.
Publicado: (2016)

Mitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanate
por: Xue, Chengsen, et al.
Publicado: (2014)

New clinical developments in histone deacetylase inhibitors for epigenetic therapy of cancer
por: Cang, Shundong, et al.
Publicado: (2009)

Dietary Phenethyl Isothiocyanate Alters Gene Expression in Human Breast Cancer Cells
por: Moon, Young Jin, et al.
Publicado: (2011)

Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models
por: Gupta, Parul, et al.
Publicado: (2012)

Phenethyl Isothiocyanate Induces Apoptosis Through ROS Generation and Caspase-3 Activation in Cervical Cancer Cells
por: Shoaib, Shoaib, et al.
Publicado: (2021)

BAG3 Protein Is Involved in Endothelial Cell Response to Phenethyl Isothiocyanate
por: Franceschelli, Silvia, et al.
Publicado: (2018)

Phenethyl isothiocyanate Triggers Apoptosis, Combats Oxidative Stress and Inhibits Growth of Ehrlich Ascites Carcinoma Mouse Model
por: Eisa, Nada H., et al.
Publicado: (2018)

Metformin and phenethyl isothiocyanate combined treatment in vitro is cytotoxic to ovarian cancer cultures
por: Chan, Daniel K, et al.
Publicado: (2012)

Nrf2 Knockout Attenuates the Anti-Inflammatory Effects of Phenethyl Isothiocyanate and Curcumin
por: Boyanapalli, Sarandeep S. S., et al.
Publicado: (2014)

Dietary Phenethyl Isothiocyanate Protects Mice from Colitis Associated Colon Cancer
por: Liu, Yi, et al.
Publicado: (2017)

Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells
por: Chou, Yu-Cheng, et al.
Publicado: (2018)

Various modes of action of dietary phytochemicals, sulforaphane and phenethyl isothiocyanate, on pathogenic bacteria
por: Nowicki, Dariusz, et al.
Publicado: (2019)

Phenethyl Isothiocyanate-Containing Carbomer Gel for Use against Squamous Cell Carcinoma
por: Osipitan, Ositomiwa O., et al.
Publicado: (2021)

Phenethyl Isothiocyanate Enhances the Cytotoxic Effects of PARP Inhibitors in High-Grade Serous Ovarian Cancer Cells
por: Jia, Yaxun, et al.
Publicado: (2022)

Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1
por: Dayalan Naidu, Sharadha, et al.
Publicado: (2018)

Phenethyl Isothiocyanate-Conjugated Chitosan Oligosaccharide Nanophotosensitizers for Photodynamic Treatment of Human Cancer Cells
por: Bae, Inho, et al.
Publicado: (2022)

Metastasis of Breast Tumor Cells to Brain Is Suppressed by Phenethyl Isothiocyanate in a Novel In Vivo Metastasis Model
por: Gupta, Parul, et al.
Publicado: (2013)

Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways
por: Gao, N, et al.
Publicado: (2011)

Notch Activation by Phenethyl Isothiocyanate Attenuates Its Inhibitory Effect on Prostate Cancer Cell Migration
por: Kim, Su-Hyeong, et al.
Publicado: (2011)

Induction of Epoxide Hydrolase, Glucuronosyl Transferase, and Sulfotransferase by Phenethyl Isothiocyanate in Male Wistar Albino Rats
por: Abdull Razis, Ahmad Faizal, et al.
Publicado: (2014)

Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical
por: Kumari, Vandana, et al.
Publicado: (2016)

C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo
por: Zhu, Q-y, et al.
Publicado: (2011)

Breast cancer cell growth inhibition by phenethyl isothiocyanate is associated with down-regulation of oestrogen receptor-α36
por: Kang, Lianguo, et al.
Publicado: (2010)

Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
por: Tan, Jiahuai, et al.
Publicado: (2010)

Lead Induces Apoptosis and Histone Hyperacetylation in Rat Cardiovascular Tissues
por: Xu, Li-Hui, et al.
Publicado: (2015)

Cisplatin in combination with Phenethyl Isothiocyanate (PEITC), a potential new therapeutic strategy for malignant pleural mesothelioma
por: Denis, Iza, et al.
Publicado: (2014)

Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth
por: Aggarwal, M, et al.
Publicado: (2016)

Mechanistic Insights into Chemopreventive Effects of Phenethyl Isothiocyanate in N‐Nitrosobis(2‐oxopropyl)amine‐treated Hamsters
por: Nishikawa, Akiyoshi, et al.
Publicado: (1997)

P-loop mutations and novel therapeutic approaches for imatinib failures in chronic myeloid leukemia
por: Cang, Shundong, et al.
Publicado: (2008)

Isothiocyanates as Tubulin Polymerization Inhibitors—Synthesis and Structure–Activity Relationship Studies
por: Grzywa, Renata, et al.
Publicado: (2023)

Phenethyl isothiocyanate upregulates death receptors 4 and 5 and inhibits proliferation in human cancer stem-like cells
por: Wang, Dan, et al.
Publicado: (2014)

Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells
por: Tusskorn, Ornanong, et al.
Publicado: (2013)

Phenethyl Isothiocyanate Exposure Promotes Oxidative Stress and Suppresses Sp1 Transcription Factor in Cancer Stem Cells
por: Upadhyaya, Bijaya, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_a3vkmbcier15llj88k4ange7ib