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Network topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approach

BACKGROUND: Accurate estimation of parameters of biochemical models is required to characterize the dynamics of molecular processes. This problem is intimately linked to identifying the most informative experiments for accomplishing such tasks. While significant progress has been made, effective exp...

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Detalles Bibliográficos
Autores principales:	Meyer, Pablo, Cokelaer, Thomas, Chandran, Deepak, Kim, Kyung Hyuk, Loh, Po-Ru, Tucker, George, Lipson, Mark, Berger, Bonnie, Kreutz, Clemens, Raue, Andreas, Steiert, Bernhard, Timmer, Jens, Bilal, Erhan, DREAM 6&7 Parameter Estimation consortium, Sauro, Herbert M, Stolovitzky, Gustavo, Saez-Rodriguez, Julio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927870/ https://www.ncbi.nlm.nih.gov/pubmed/24507381 http://dx.doi.org/10.1186/1752-0509-8-13

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