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Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt-tRNA mutations

Disorders of the mitochondrial genome cause a wide spectrum of disease, these present mainly as neurological and/or muscle related pathologies. Due to the intractability of the human mitochondrial genome there are currently no effective treatments for these disorders. The majority of the pathogenic...

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Detalles Bibliográficos
Autores principales:	Hornig-Do, Hue Tran, Montanari, Arianna, Rozanska, Agata, Tuppen, Helen A, Almalki, Abdulraheem A, Abg-Kamaludin, Dyg P, Frontali, Laura, Francisci, Silvia, Lightowlers, Robert N, Chrzanowska-Lightowlers, Zofia M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927954/ https://www.ncbi.nlm.nih.gov/pubmed/24413189 http://dx.doi.org/10.1002/emmm.201303202

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