ADAM17 mediates OSCC development in an orthotopic murine model

BACKGROUND: ADAM17 is one of the main sheddases of the cells and it is responsible for the cleavage and the release of ectodomains of important signaling molecules, such as EGFR ligands. Despite the known crosstalk between ADAM17 and EGFR, which has been considered a promising targeted therapy in or...

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Detalles Bibliográficos
Autores principales: Simabuco, Fernando Moreira, Kawahara, Rebeca, Yokoo, Sami, Granato, Daniela C, Miguel, Lucas, Agostini, Michelle, Aragão, Annelize ZB, Domingues, Romênia R, Flores, Isadora L, Macedo, Carolina CS, Coletta, Ricardo Della, Graner, Edgard, Paes Leme, Adriana Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928084/
https://www.ncbi.nlm.nih.gov/pubmed/24495306
http://dx.doi.org/10.1186/1476-4598-13-24

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