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ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response
BACKGROUND: Neuropathic pain is a difficult to treat disorder arising from central or peripheral nervous system lesions. The etiology of neuropathic pain consists of several overlapping pathways converging into an exaggerated pain state with symptoms such as allodynia and hyperalgesia. One of these...
Autores principales: | Swartjes, Maarten, van Velzen, Monique, Niesters, Marieke, Aarts, Leon, Brines, Michael, Dunne, Ann, Cerami, Anthony, Dahan, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928087/ https://www.ncbi.nlm.nih.gov/pubmed/24529189 http://dx.doi.org/10.1186/1744-8069-10-13 |
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