A Novel Mutation of Hyaluronan Synthase 2 Gene in Chinese Children with Ventricular Septal Defect

As a major product of extracellular matrix (ECM), Hyaluronic acid (HA) is involved in early cardiac development and mainly synthesized by Hyaluronan synthase 2 (HAS2) during embryogenesis. Targeted deletion of HAS2 gene in mice led to obvious cardiac and vascular defects. To clarify the potential as...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Xiaomei, Deng, Xiaopeng, Huang, Guangying, Wang, Jing, Yang, Jingwen, Chen, Si, Ma, Xu, Wang, Binbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928120/
https://www.ncbi.nlm.nih.gov/pubmed/24558368
http://dx.doi.org/10.1371/journal.pone.0087437

Ejemplares similares

Ejemplares similares