Differential Blood and Mucosal Immune Responses against an HIV-1 Vaccine Administered via Inguinal or Deltoid Injection

Mucosal immunity is central to sexual transmission and overall pathogenesis of HIV-1 infection, but the ability of vaccines to induce immune responses in mucosal tissue compartments is poorly defined. Because macaque vaccine studies suggest that inguinal (versus limb) vaccination may better target s...

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Detalles Bibliográficos
Autores principales: Yang, Otto O., Ibarrondo, F. Javier, Price, Charles, Hultin, Lance E., Elliott, Julie, Hultin, Patricia M., Shih, Roger, Hausner, Mary Ann, Ng, Hwee L., Hoffman, Jennifer, Jamieson, Beth D., Anton, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928250/
https://www.ncbi.nlm.nih.gov/pubmed/24558403
http://dx.doi.org/10.1371/journal.pone.0088621

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