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Influence of Radiologically Evident Residual Intimal Tear on Expansion of Descending Aorta Following Surgery for Acute Type I Aortic Dissection

BACKGROUND: Although a residual intimal tear may contribute to the dilatation of the descending aorta following surgical repair of acute type I aortic dissection (AD), its causal relationship has not been elucidated by clinical data due to the limited resolution of imaging modalities. METHODS: This...

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Autores principales: Kim, Yun Seok, Kim, Jeong Heon, Kim, Joon Bum, Yang, Dong Hyun, Kang, Joon-Won, Hwang, Su Kyung, Choo, Suk Jung, Chung, Cheol Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Thoracic and Cardiovascular Surgery 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928268/
https://www.ncbi.nlm.nih.gov/pubmed/24570859
http://dx.doi.org/10.5090/kjtcs.2014.47.1.6
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author Kim, Yun Seok
Kim, Jeong Heon
Kim, Joon Bum
Yang, Dong Hyun
Kang, Joon-Won
Hwang, Su Kyung
Choo, Suk Jung
Chung, Cheol Hyun
author_facet Kim, Yun Seok
Kim, Jeong Heon
Kim, Joon Bum
Yang, Dong Hyun
Kang, Joon-Won
Hwang, Su Kyung
Choo, Suk Jung
Chung, Cheol Hyun
author_sort Kim, Yun Seok
collection PubMed
description BACKGROUND: Although a residual intimal tear may contribute to the dilatation of the descending aorta following surgical repair of acute type I aortic dissection (AD), its causal relationship has not been elucidated by clinical data due to the limited resolution of imaging modalities. METHODS: This study enrolled 41 patients (age, 55.2±11.9 years) who were evaluated with dual-source computed tomography (CT) imaging of the whole aorta in the setting of the surgical repair of acute type I AD. Logistic regression models were used to determine the predictors of a composite of the aortic aneurysm formation (diameter >55 mm) and rapid aortic expansion (>5 mm/yr). RESULTS: On initial CT, a distal re-entry tear was identified in 9 patients. Two patients failed to achieve proximal tear exclusion by the surgery. Serial follow-up CT evaluations (median, 24.6 months; range, 6.0 to 67.2 months) revealed that 14 patients showed rapid expansion of the descending aorta or aortic aneurysm formation. A multivariate analysis revealed that the residual intimal tear (odds ratio [OR], 4.31; 95% confidence interval [CI], 1.02 to 19.31) and the patent false lumen in the early postoperative setting (OR, 4.64; 95% CI, 0.99 to 43.61) were predictive of the composite endpoint. CONCLUSION: The presence of a residual intimal tear following surgery for acute type I AD adversely influenced the expansion of the descending aorta.
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spelling pubmed-39282682014-02-25 Influence of Radiologically Evident Residual Intimal Tear on Expansion of Descending Aorta Following Surgery for Acute Type I Aortic Dissection Kim, Yun Seok Kim, Jeong Heon Kim, Joon Bum Yang, Dong Hyun Kang, Joon-Won Hwang, Su Kyung Choo, Suk Jung Chung, Cheol Hyun Korean J Thorac Cardiovasc Surg Clinical Research BACKGROUND: Although a residual intimal tear may contribute to the dilatation of the descending aorta following surgical repair of acute type I aortic dissection (AD), its causal relationship has not been elucidated by clinical data due to the limited resolution of imaging modalities. METHODS: This study enrolled 41 patients (age, 55.2±11.9 years) who were evaluated with dual-source computed tomography (CT) imaging of the whole aorta in the setting of the surgical repair of acute type I AD. Logistic regression models were used to determine the predictors of a composite of the aortic aneurysm formation (diameter >55 mm) and rapid aortic expansion (>5 mm/yr). RESULTS: On initial CT, a distal re-entry tear was identified in 9 patients. Two patients failed to achieve proximal tear exclusion by the surgery. Serial follow-up CT evaluations (median, 24.6 months; range, 6.0 to 67.2 months) revealed that 14 patients showed rapid expansion of the descending aorta or aortic aneurysm formation. A multivariate analysis revealed that the residual intimal tear (odds ratio [OR], 4.31; 95% confidence interval [CI], 1.02 to 19.31) and the patent false lumen in the early postoperative setting (OR, 4.64; 95% CI, 0.99 to 43.61) were predictive of the composite endpoint. CONCLUSION: The presence of a residual intimal tear following surgery for acute type I AD adversely influenced the expansion of the descending aorta. Korean Society for Thoracic and Cardiovascular Surgery 2014-02 2014-02-05 /pmc/articles/PMC3928268/ /pubmed/24570859 http://dx.doi.org/10.5090/kjtcs.2014.47.1.6 Text en © The Korean Society for Thoracic and Cardiovascular Surgery. 2014. All right reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Kim, Yun Seok
Kim, Jeong Heon
Kim, Joon Bum
Yang, Dong Hyun
Kang, Joon-Won
Hwang, Su Kyung
Choo, Suk Jung
Chung, Cheol Hyun
Influence of Radiologically Evident Residual Intimal Tear on Expansion of Descending Aorta Following Surgery for Acute Type I Aortic Dissection
title Influence of Radiologically Evident Residual Intimal Tear on Expansion of Descending Aorta Following Surgery for Acute Type I Aortic Dissection
title_full Influence of Radiologically Evident Residual Intimal Tear on Expansion of Descending Aorta Following Surgery for Acute Type I Aortic Dissection
title_fullStr Influence of Radiologically Evident Residual Intimal Tear on Expansion of Descending Aorta Following Surgery for Acute Type I Aortic Dissection
title_full_unstemmed Influence of Radiologically Evident Residual Intimal Tear on Expansion of Descending Aorta Following Surgery for Acute Type I Aortic Dissection
title_short Influence of Radiologically Evident Residual Intimal Tear on Expansion of Descending Aorta Following Surgery for Acute Type I Aortic Dissection
title_sort influence of radiologically evident residual intimal tear on expansion of descending aorta following surgery for acute type i aortic dissection
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928268/
https://www.ncbi.nlm.nih.gov/pubmed/24570859
http://dx.doi.org/10.5090/kjtcs.2014.47.1.6
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