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Respiratory Syncytial Virus (RSV) Infection in Elderly Mice Results in Altered Antiviral Gene Expression and Enhanced Pathology

Elderly persons are more susceptible to RSV-induced pneumonia than young people, but the molecular mechanism underlying this susceptibility is not well understood. In this study, we used an aged mouse model of RSV-induced pneumonia to examine how aging alters the lung pathology, modulates antiviral...

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Detalles Bibliográficos
Autores principales: Wong, Terianne M., Boyapalle, Sandhya, Sampayo, Viviana, Nguyen, Huy D., Bedi, Raminder, Kamath, Siddharth G., Moore, Martin L., Mohapatra, Subhra, Mohapatra, Shyam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928298/
https://www.ncbi.nlm.nih.gov/pubmed/24558422
http://dx.doi.org/10.1371/journal.pone.0088764

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