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Long-Term Activation upon Brief Exposure to Xanomleline Is Unique to M(1) and M(4) Subtypes of Muscarinic Acetylcholine Receptors
Xanomeline is an agonist endowed with functional preference for M(1)/M(4) muscarinic acetylcholine receptors. It also exhibits both reversible and wash-resistant binding to and activation of these receptors. So far the mechanisms of xanomeline selectivity remain unknown. To address this question we...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928307/ https://www.ncbi.nlm.nih.gov/pubmed/24558448 http://dx.doi.org/10.1371/journal.pone.0088910 |