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Thiol/Redox Metabolomic Profiling Implicates GSH Dysregulation in Early Experimental Graft versus Host Disease (GVHD)
Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation (BMT). Upregulation of inflammatory cytokines precedes the clinical presentation of GVHD and predicts its severity. In this report, thiol/redox metabolomics was used to identify metabolic perturbation...
Autores principales: | Suh, Jung H., Kanathezhath, Bindu, Shenvi, Swapna, Guo, Hua, Zhou, Alicia, Tiwana, Anureet, Kuypers, Frans, Ames, Bruce N., Walters, Mark C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928313/ https://www.ncbi.nlm.nih.gov/pubmed/24558439 http://dx.doi.org/10.1371/journal.pone.0088868 |
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