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RPEL Proteins Are the Molecular Targets for CCG-1423, an Inhibitor of Rho Signaling
Epithelial–msenchymal transition (EMT) is closely associated with cancer and tissue fibrosis. The nuclear accumulation of myocardin-related transcription factor A (MRTF-A/MAL/MKL1) plays a vital role in EMT. In various cells treated with CCG-1423, a novel inhibitor of Rho signaling, the nuclear accu...
Autores principales: | Hayashi, Ken’ichiro, Watanabe, Bunta, Nakagawa, Yoshiaki, Minami, Saki, Morita, Tsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928398/ https://www.ncbi.nlm.nih.gov/pubmed/24558465 http://dx.doi.org/10.1371/journal.pone.0089016 |
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