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RRP6 from Trypanosoma brucei: Crystal Structure of the Catalytic Domain, Association with EAP3 and Activity towards Structured and Non-Structured RNA Substrates

RRP6 is a 3′–5′ exoribonuclease associated to the eukaryotic exosome, a multiprotein complex essential for various RNA processing and degradation pathways. In Trypanosoma brucei, RRP6 associates with the exosome in stoichiometric amounts and was localized in both cytoplasm and nucleus, in contrast t...

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Detalles Bibliográficos
Autores principales:	Barbosa, Rosicler L., Legrand, Pierre, Wien, Frank, Pineau, Blandine, Thompson, Andrew, Guimarães, Beatriz G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928423/ https://www.ncbi.nlm.nih.gov/pubmed/24558481 http://dx.doi.org/10.1371/journal.pone.0089138

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