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Otx2 ChIP-seq Reveals Unique and Redundant Functions in the Mature Mouse Retina
During mouse retinal development and into adulthood, the transcription factor Otx2 is expressed in pigment epithelium, photoreceptors and bipolar cells. In the mature retina, Otx2 ablation causes photoreceptor degeneration through a non-cell-autonomous mechanism involving Otx2 function in the suppor...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928427/ https://www.ncbi.nlm.nih.gov/pubmed/24558479 http://dx.doi.org/10.1371/journal.pone.0089110 |