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Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Management in Streptococcus pneumoniae
Streptococcus pneumoniae requires manganese for colonization of the human host, but the underlying molecular basis for this requirement has not been elucidated. Recently, it was shown that zinc could compromise manganese uptake and that zinc levels increased during infection by S. pneumoniae in all...
Autores principales: | Eijkelkamp, Bart A., Morey, Jacqueline R., Ween, Miranda P., Ong, Cheryl-lynn Y., McEwan, Alastair G., Paton, James C., McDevitt, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928430/ https://www.ncbi.nlm.nih.gov/pubmed/24558498 http://dx.doi.org/10.1371/journal.pone.0089427 |
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