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Chondrocyte-Specific Inhibition of β-Catenin Signaling Leads to Dysplasia of the Caudal Vertebrae in Mice

STUDY DESIGN. To inhibit β-catenin specifically signaling in chondrocytes Col2-ICAT transgenic mice were generated. Anomalies in caudal vertebrae were detected during embryonic and postnatal stages of Col2-ICAT transgenic mice. OBJECTIVE. To determine the role of canonical β-catenin signaling in cau...

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Detalles Bibliográficos
Autores principales:	Shu, Bing, Li, Tian-Fang, Li, Xiao-Feng, Tang, De-Zhi, Zhang, Yejia, Shi, Qi, Wang, Yong-Jun, Chen, Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2013
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928445/ https://www.ncbi.nlm.nih.gov/pubmed/24026150 http://dx.doi.org/10.1097/01.brs.0000435024.57940.8d

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