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Causal analysis approaches in Ingenuity Pathway Analysis
Motivation: Prior biological knowledge greatly facilitates the meaningful interpretation of gene-expression data. Causal networks constructed from individual relationships curated from the literature are particularly suited for this task, since they create mechanistic hypotheses that explain the exp...
Autores principales: | Krämer, Andreas, Green, Jeff, Pollard, Jack, Tugendreich, Stuart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928520/ https://www.ncbi.nlm.nih.gov/pubmed/24336805 http://dx.doi.org/10.1093/bioinformatics/btt703 |
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