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forqs: forward-in-time simulation of recombination, quantitative traits and selection

Summary: forqs is a forward-in-time simulation of recombination, quantitative traits and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations due to recombination and/or selection...

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Detalles Bibliográficos
Autores principales: Kessner, Darren, Novembre, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928523/
https://www.ncbi.nlm.nih.gov/pubmed/24336146
http://dx.doi.org/10.1093/bioinformatics/btt712
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author Kessner, Darren
Novembre, John
author_facet Kessner, Darren
Novembre, John
author_sort Kessner, Darren
collection PubMed
description Summary: forqs is a forward-in-time simulation of recombination, quantitative traits and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations due to recombination and/or selection on polygenic quantitative traits. Availability and implementation: forqs is implemented as a command-line C++ program. Source code and binary executables for Linux, OSX and Windows are freely available under a permissive BSD license: https://bitbucket.org/dkessner/forqs. Contact: jnovembre@uchicago.edu Supplementary information: Supplementary data are available at Bioinformatics online.
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spelling pubmed-39285232014-02-24 forqs: forward-in-time simulation of recombination, quantitative traits and selection Kessner, Darren Novembre, John Bioinformatics Applications Notes Summary: forqs is a forward-in-time simulation of recombination, quantitative traits and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations due to recombination and/or selection on polygenic quantitative traits. Availability and implementation: forqs is implemented as a command-line C++ program. Source code and binary executables for Linux, OSX and Windows are freely available under a permissive BSD license: https://bitbucket.org/dkessner/forqs. Contact: jnovembre@uchicago.edu Supplementary information: Supplementary data are available at Bioinformatics online. Oxford University Press 2014-02-15 2013-12-10 /pmc/articles/PMC3928523/ /pubmed/24336146 http://dx.doi.org/10.1093/bioinformatics/btt712 Text en © The Author 2013. Published by Oxford University Press. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Kessner, Darren
Novembre, John
forqs: forward-in-time simulation of recombination, quantitative traits and selection
title forqs: forward-in-time simulation of recombination, quantitative traits and selection
title_full forqs: forward-in-time simulation of recombination, quantitative traits and selection
title_fullStr forqs: forward-in-time simulation of recombination, quantitative traits and selection
title_full_unstemmed forqs: forward-in-time simulation of recombination, quantitative traits and selection
title_short forqs: forward-in-time simulation of recombination, quantitative traits and selection
title_sort forqs: forward-in-time simulation of recombination, quantitative traits and selection
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928523/
https://www.ncbi.nlm.nih.gov/pubmed/24336146
http://dx.doi.org/10.1093/bioinformatics/btt712
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